000			03358fam a2200361 a 4500
001			4016705
003			OSt
005			20170822174959.0
008			940523s1995 moua b 001 0 eng c
010			_a 94013013
020			_a0801664144
035			_a(OCoLC)30624793
035			_a(OCoLC)ocm30624793
035			_a(NNC)4016705
040			_aDNLM/DLC _cBSU _dDLC _dNNC-M
050	0	0	_aRB155 _b.J67 1995
060	1	0	_aQZ 50 J82m 1995
082	0	0	_a616.042 JOR _222
100	1		_aJorde, Lynn B. _915670
245	1	0	_aMedical genetics / _cLynn B. Jorde, John C. Carey, Raymond L. White.
260			_aSt. Louis : _bMosby, _cc1995.
300			_ax, 293 p. : _bill. ; _c28 cm.
504			_aIncludes bibliographical references and index.
505	0		_a1. Introduction. What is Medical Genetics? Why is a Knowledge of Medical Genetics Important for Today's Practicing Physician? A Brief History. Types of Genetic Diseases. Clinical Impact of Genetic Disease -- 2. Basic Cell Biology: Structure and Function of Genes and Chromosomes. DNA, RNA, and Proteins: Heredity at the Molecular Level. The Structure of Genes and the Genome. The Cell Cycle -- 3. Genetic Variation: Its Origin and Detection. Mutation: The Source of Genetic Variation. Detection and Measurement of Genetic Variation -- 4. Autosomal Dominant and Recessive Inheritance. Basic Concepts of Formal Genetics. Autosomal Dominant Inheritance. Autosomal Recessive Inheritance. Factors that may Complicate Inheritance Patterns. Consanguinity in Human Populations -- 5. Sex-Linked and Mitochondrial Inheritance. X Inactivation. Sex-Linked Inheritance. Sex-Limited and Sex-Influenced Traits. Mitochondrial Inheritance -- 6. Clinical Cytogenetics: The Chromosomal Basis of Human Disease.
505	0		_aCytogenetic Technology and Nomenclature. Abnormalities of Chromosome Number. Chromosome Abnormalities and Pregnancy Loss. Abnormalities of Chromosome Structure. Chromosome Abnormalities and Clinical Phenotypes. Cancer Cytogenetics. Chromosome Instability Syndromes -- 7. Gene Mapping. Genetic Mapping. Physical Mapping. Progress Toward a Complete Human Map -- 8. Immunogenetics. The Immune Response: Basic Concepts. Immune Response Proteins: Genetic Basis of Structure and Diversity. The Major Histocompatibility Complex. The ABO and Rh Blood Groups. Immunodeficiency Diseases -- 9. Cancer Genetics. Causes of Cancer. Inherited Cancer Genes. Identification of Inherited Cancer Genes. Molecular Basis of Cancer. Is Genetic Inheritance Important in Common Cancers? -- 10. Multifactorial Inheritance and Common Disease. Principles of Multifactorial Inheritance. Nature and Nurture: Disentangling the Effects of Genes and Environment. The Genetics of Common Diseases.
505	0		_a11. Genetic Screening, Genetic Diagnosis, and Gene Therapy. Population Screening for Genetic Disease. Molecular Tools for Screening and Diagnosis. Prenatal Diagnosis of Genetic Disorders and Congenital Defects. Fetal Treatment. Gene Therapy -- 12. Clinical Genetics and Genetic Counseling. The Principles and Practices of Clinical Genetics. Dysmorphology and Clinical Teratology.
650		0	_aMedical genetics. _915671
650		2	_aGenetic Diseases, Inborn _xgenetics. _915672
700	1		_aCarey, John C., _d1946- _915673
700	1		_aWhite, Raymond L., _d1943- _915674
942			_2ddc _cBK
999			_c7268 _d7268