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008			220222t20192019enka b 001 0 eng c
010			_a 2021277753
016	7		_a101739947 _2DNLM
020			_a9780128122020
020			_a0128122021
035			_a(OCoLC)on1066038534
040			_aNLM _beng _cNLM _erda _dGSU _dOCLCF _dYDX _dOCLCO _dOCLCA _dOCLCO _dDLC
042			_apcc
050	0	0	_aRC341 _b.N357 2019
060	0	0	_a2019 A-436
060	1	0	_aWM 270
082			_a617.9 _bNEU
245	0	0	_aNeural mechanisms of addiction / _c[edited by] Mary Torregrossa.
260			_aLondon : _bElsevier/Academic Press, _c[2019]
300			_axii, 294 pages : _billustrations ; _c28 cm
504			_aIncludes bibliographical references and index.
505	0		_aIntroduction to the neural basis of addiction -- Animal models of addiction -- Transcriptional and epigenetic regulation and reward circuitry in drug addiction -- Neural circuit plasticity in addiction -- Glutamatergic neuroplasticity in addiction -- Fos-expressing neuronal ensembles in addiction research -- Interoceptive stimulus effects of drugs of abuse -- Maladaptive memory mechanisms in addiction and relapse -- Neural morphology and addiction -- Mechanisms regulating compulsive drug behaviors -- Role of stress-associated signaling in addiction -- Negative reinforcement mechanisms in addiction -- Circadian rhythms and addiction -- Role of Oxytocin in countering addiction-associated behaviors exacerbated by stress -- The role of norepinephrine in drug addiction: past, present, and future -- Glial disregulation in addiction -- Role of the extracellular matrix in addiction -- Striatal cell-tyle specific plasticity in addiction -- Harnessing circuits for the treatment of addictive disorders -- Conclusions and future directions.
520			_aNeural Mechanisms of Addiction is the only book available that synthesizes the latest research in the field into a single, accessible resource covering all aspects of how addiction develops and persists in the brain. The book summarizes our most recent understanding on the neural mechanisms underlying addiction. It also examines numerous biobehavioral aspects of addiction disorders, such as reinforcement learning, reward, cognitive dysfunction, stress, and sleep and circadian rhythms that are not covered in any other publication. Readers with find the most up-to-date information on which to build a foundation for their future research in this expanding field. Combining chapters from leading researchers and thought leaders, this book is an indispensable guide for students and investigators engaged in addiction research.
650		0	_aNeuropsychiatry. _923891
650		0	_aDrug addiction _xPhysiological aspects. _923892
650	1	2	_aSubstance-Related Disorders _xphysiopathology _923893
650	2	2	_aBrain _xdrug effects _923894
650	2	2	_aBrain _xphysiopathology _923895
650		6	_aNeuropsychiatrie. _923896
650		6	_aToxicomanie _xAspect physiologique. _923897
650		7	_aDrug addiction _xPhysiological aspects. _2fast _923892
650		7	_aNeuropsychiatry. _2fast _923891
700	1		_aTorregrossa, Mary, _eeditor. _923898
776	0	8	_iElectronic version: _aTorregrossa, Mary. _tNeural mechanisms of addiction. _dLondon : Academic Press, 2019 _z9780128123317 _w(OCoLC)1050163125
906			_a7 _bcbc _cpccadap _d2 _encip _f20 _gy-gencatlg
942			_2ddc _cBK
999			_c12402 _d12402