Physiology of the gastrointestinal tract / editor-in-chief, Hamid M. Said, Department of Medicine and Physiology/Biophysics, University of California School of Medicine, Irvine, California, USA.

Includes bibliographical references and index

V.I. Sect. I. Basic cell physiology, genetics, and growth of the GI tract. Transcription and epigenetic regulation / Juanita L. Merchant -- Post-translational processing of gastrointestinal peptides / Graham S. Baldwin -- Genetic tools in gastrointestinal diseases / Clara Abraham and Judy Cho -- Signaling pathways induced by G-protein-coupled receptors / Enrique Rozengurt -- Transgenic animal models of gastrointestinal function / Marie-Pier Tetreault and Jonathan P. Katz -- Gastrointestinal function / Marie-Pier Tetreault and Jonathan P. Katz -- Gastrointestinal peptides: gastrin, cholecystokinin, somatostatin, and ghrelin / Celia Chao and Mark R. Hellmich -- Postpyloric gastrointestinal peptides / Guillermo A. Ggomez, Ella W. Englander, and George H. Greeley, Jr. -- Growth factors in the gastrointestinal tract / John F. Kuemmerle -- Developmental signaling networks: WNT/[beta]-catenin signaling in the gastrointestinal tract / Guido T. Bommer and Eric R. Fearon -- Hedgehog signaling in gastrointestinal morphogenesis and morphostasis / Willemijn A. van Dop and Gijs R. van den Brink -- Notch pathway regulation of intestinal cell fate / Kelli L. Van Dussen, Peter J. Dempsey, and Linda C. Samuelson

Stem cells in the gastrointestinal tract / Nicholas A. Wright -- Programmed cell death in the gastrointestinal tract / Leonard R. Johnson and Ramesh M. Ray -- Molecular physiology of gastrointestinal function during development / Hua Xu, James F. Collins, and Fayez K. Ghishan -- The cell cycle / Vincent W. Yang -- Sect. II. Neurogastroenterology. Development of the enteric nervous system / Heather M. Young, Donald F. Newgreen, and Hideki Enomoto -- Cellular physiology of gastrointestinal smooth muscle / Khalil N. Bitar [and others] -- Organization and electrophysiology of interstitial cells of cajal and smooth muscle cells in the gastrointestinal tract / Kenton M. Sanders, Sang Don Koh, and Sean M. Ward -- Enteric nervous system structure and neurochemistry related to function and neuropathology / Daniel P. Poole and John B. Furness -- Physiology of prevertebral sympathetic ganglia / Joseph H. Szurszewski and David R. Linden -- Cellular neurophysiology of enteric neurons / Jackie D. Wood -- Integrative functions of the enteric nervous system / Jackie D. Wood -- Processing of gastrointestinal sensory signals in the brain / Steven J. Coen, Anthony R. Hobson, and Qasim Aziz

Innervation of the gastrointestinal tract by spinal and vagal afferent nerves / Stuart M. Brierley [and others] -- Neuroimaging of brain-gut interactions in functional gastrointestinal disorders / Kirsten Tillisch [and others] -- The neurobiology of gustation: taste buds and transduction processes / Scott Herness -- Enteric neural regulation of mucosal secretion / Joel C. Bornstein, Rachel M. Gwynne, and Henrik Sjövall -- Hypothalamic-pituitary-adrenal axis in gastrointestinal physiology / Shin Fukudo -- Neural regulation of gastrointestinal blood flow / Peter Holzer -- Neuromuscular function in the biliary tract / Gary M. Mawe [and others] -- Brainstem control of the gastric function / Richard C. Rogers and Gerlinda E. Hermann -- Physiology of aerodigestive reflexes in neonates and adults / Sudarshan R. Jadcherla and Reza Shaker -- Motor function of the pharynx, the esophagus, and its sphincters / Ravinder K. Mittal -- Neurophysiologic mechanisms of gastric reservoir function / Jan Tack -- Physiology of the antral pump and gastric emptying / Christopher K. Rayner, Geoffrey S. Hebbard, and Michael Horowitz -- Neurophysiologic mechanisms of human large intestinal motility / Adil E. Bharucha and Simon J.H. Brookes

Neuromuscular physiology of the pelvic floor / Arnold Wald -- Sect. III. Host defense mechanisms. tight junctions and theintestinal barrier / Thomas Y. ma, James M. Anderson, and Jerrold R. Turner -- Biology of gut immunoglobulins / Finn-Eirik Johansen [and others] -- Gastrointestinal microbial ecology with perspectives on health and disease / Merritt G. Gillilland, vincent B. Young, and Gary B. Huffnagle -- Mucsoal bacterial recognition and signaling systems in the intestine / masayuki Fukata and Maria T. Abreu -- Mucosal restitution and repair / D. Brent Polk and Mark R. Frey -- Gastroduodenal mucosal defense / Maggie Ham [and others] -- V. II. Sect. IV. Physiology of secretion. Paneth cells / André J. Ouellette -- Salivary gland secretion / Marcelo A. Catalán, Kiran S. Ambatipudi, and James E. Melvin -- The cell biology of gastric acid secretion / Curtis Okamoto [and others] -- Regulation of gastric acid secretion / Mitchell L. schubert -- Gastroduodenal bicarbonate secretion / Ursula Seidler and Markus Sjöblom -- Structure-function relationships in the pancreatic acinar cell / Fred S. Gorelick and James D. Jamieson -- Stimulus-secretion coupling in pancreatic acinar cells / John A. Williams and David I. Yule

Cell physiology of pancreatic ducts / Barry E. Argent [and others] -- Regulation of pancreatic secretion / Rodger A. Liddle -- Bile formation and the enterohepatic circulation / Paul A. Dawson -- Mechanisms of hepatocyte organic anion transport / Allan W. Wolkoff -- Mechanisms of hepatocyte detoxification / Donald J. Messner, Karen F. Murray, and Kris V. Kowdley -- Sect. V. Digestion and absorption. Physiology of cholangiocytes / Anatoliy I. Masyuk, Tatyana V. Masyuk, and Nicholas F. LaRusso -- Molecular mechanisms of protein sorting in polarized epithelial cells / Bernardo Ortega and Paul A. Welling -- Sugar absorption / Ernest M. Wright [and others] -- Protein digestion andabsorption / Vadivel Ganapathy -- Enterocyte fatty acid handling proteins and chylomicron formation / Charles M. Mansbach, II and Nada A. Abumrad -- Genetic regulation of intestinal lipid transport and metabolism / Zhouji Chen and Nicholas O. Davidson -- Digestion and intestinal absorption of dietary carotenoids and vitamin A / Earl H. Harrison -- 1,25-dihydroxyvitamin D3: synthesis, actions, and genome-scale mechanisms in the intestine and colon /J. Wesley Pike and Mark B. Meyer

Mechanisms and regulation of intestinal absorption of water-soluble vitamins: cellular and molecular aspects / Hamid M. Said and Ebba Nexo -- Water transport in the gastrointestinal tract / Jay R. Thiagarajah and A.S. Verkman -- Na+/H+ exchange in mammalian digestive tract / Pawel R. Kiela and Fayez K. Ghishan -- Intestinal antion absorption / Ravinder K. Gill [and others] -- cAMP sensor epac and gastrointestinal function / Oleg G. Chepurny [and others] -- Ion channels of the epithelia of the gastrointestinal tract / John Cuppoletti and Danuta H. Malinowska -- Molecular mechanisms of intestinal transport of calcium, phosphate, and magnesium / Pawel R. Kiela, James F. Collins, and Fayez K. Ghishan -- Molecular mechanisms of intestinal iron transport / James F. Collins and Gregory J. Anderson -- Sect. VI. Consequences of disregulated physiology. Trace element absorption and transport / Robert J. Cousins -- The gastrointestinal tract and control of food intake / Guillaume de Lartigue and Helen E. Raybould -- Effects of stress on intestinal mucosal functions / Johan D. Söderholm -- Enteric neurobiology of stress / Sumei Liu and Jackie D. Wood

Mechanisms of helicobacter pylori-induced gastric inflammation / Dawn A. Israel and Richard M. Peek, Jr. -- Physiology of host-pathogen interactions / Kim Hodges and Gail Hecht -- Mechanisms and consequences of intestinal inflammation / Derek M. McKay and Wallace K. MacNaughton -- Recruitment of inflammatory and immune cells in the gut: physiology and pathophysiology / D. Neil Granger, Christopher G. Kevil, and Matthew B. Grisham -- Mechanisms of GI malignancies /John P. Lynch and Anil K. Rustgi -- Pathophysiology underlying the irritable bowel syndrome / Jackie D. Wood -- Pathophysiology of diarrhea and its clinical implications / Rana F. Ammoury and Fayez K. Ghishan

"The gastrointestinal system is responsible for the breakdown and absorption of various foods and liquids needed to sustain life. Other diseases and disorders treated by clinicians in this area include: food allergies, constipation, chronic liver disease and cirrhosis, gallstones, gastritis, GERD, hemorrhoids, IBS, lactose intolerance, pancreatic, appendicitis, celiac disease, Crohns disease, peptic ulcer, stomach ulcer, viral hepatitis, colorectal cancer and liver transplants. Physiology of the Gastrointestinal Tract, 5/e covers the study of the mechanical, physical, and biochemical functions of the GI Tract while linking the clinical disease or disorder, bridging the gap between clinical and laboratory medicine. The new edition is a highly referenced and useful resource for gastroenterologists, physiologists, internists, professional researchers, and instructors teaching courses for clinical and research students."--Publisher's website